The neural mechanisms underlying skill acquisition will essentially be the same for a paraplegic as someone who is not.  Spinal cord injury leading to paraplegia is a physical disability and does not usually result in cognitive deficits.

 However, we would expect to see some differences among individuals with paraplegia in terms of synaptic connections.  Since wheelchair athletes require more upper body strength to shoot the ball and to move their chair there may be more neural pathways from the brain to activate the upper body muscles.  We would expect the connections to be more plentiful and stronger resulting in more efficient motor unit recruitment and force production in the upper body.

The primary motor and somatosensory strips contain a "map" of our bodies relative to the amount of input and output that structure receives.  This "map" is know as the homunculus.  In someone who has not ascending or descending messages to or from their lower body, we may expect the homunculus to change as a reflection of the changing inputs and outputs.  For example, the legs and feet area my become less active, while the trunk and arms will be more fully represented.