Repicol - English

TISSUE REGENERATOR
STIMULANT IN CICATRIZATION

CONTRAINDICATIONS:
REPICOL is contraindicated in persons that have demostrated hypersensibility to any of the components of the formula.
Do not use on patients with respiratory or renal deficiencies or immunity deficiencies.
Do not apply simultaneously with steroids due to the fact that it is an antagonist.
Do not apply bandages because they revert the scarring process.

WARNINGS:
REPICOL must not be used during pregnancy or lactation.

SIDE EFFECTS:
In rare occasions itch and burning sensation have appeared, these reactions are benign and exceptional.

HOW TO USE:
Wash the wound with water and sterile soap or a physiological solution.
Dry the wound with a sterile gauze.
Apply REPICOL to the entire affected surface and cover completely wound in order that the effect can be homogenous.
A dark brown colored film (scab) is formed and is well adhered.
The scab is cut piece by piece as it starts to detach using sterile scissors.

DIRECTIONS:
Pour sufficient powder on the wound once a day or follow your doctor's advice.

WARNINGS AND RELATIONSHIP WITH
CARCINOGENESIS EFFECTS:
Have not been reported up to date.

FORM OF APLICATION:
Cutaneous.

PRESENTATION:
Flask with 15g. of powder.

RECOMENDATIONS:
Store in a dry and cool place.
The sale of this product requires medical prescription.
Keep this product out of th reach of children.
Avoid contact with the eyes..

The impact caused with REPICOL is surprising because the majority of the patients have reacted favorably in a very short time. REPICOL constitutes one of the biggest advances of the century.

FORMULA EACH 100g. HAS :

PHENOL ----------------------------------------- 45 g
D-OXIMETHYL I-D ---------------------------- 30 g
PYROGALLIC ---------------------------------- 10 g
HEXAHYDROXYLDIPHENIC ACID ----- 10 g
FLAVIN 3-4 DIOL ----------------------------- 4.2 g
ESSENCE OILS ------------------------------ 0.8 g

INDICATIONS:
REPICOL is indicated as an epithelization agent or stimulant for the cicatrization of ulcers, wounds, traumatic injuries, burns and varicose ulcers. The effect of REPICOL is optimum if it is applied on wounds, cutaneous ulcers and on burns where there is no infection. The medication has no effect on dry wounds or scabs.

DESCRIPTION:
REPICOL is a hydrophilic amorphous powder with particles in a diameter size of 0.2 to 0.4 mm. It is chemically inert and absorbs 6 to 8 times its weight in exudates from wounds. It is dark brown in color and has the property of fixing and precipitating iron and proteins.

PHARMACOKINETICS AND PHARMACODYNAMICS:
It has been demostrated that upon application of REPICOL on wounds it is depolymerized by the action of the lysosomal enzymes wich are abundant at the site of the injury, thus permitting the formation of fibroblasts and consequently, the collagenous fibers. The effective use of REPICOL in the healing process of burn wounds is related to the composition of the connective tissue itself, that is characterized for its variable content of glycanuos- glucoamides associated with proteins. The histochemical studies performed repert that the production and deposit of mucopolysaccharides prepare and direct the fibroblasts to produce collagen whose orientation and crossing will depend on the mechanical properties of the scared tissue.
REPICOL has a close relation with collagen and an angiogenic factor that precipitates the proteins and adheres to the cellular necrotic detritus tissue and tampons the blood vessels preventing bleeding and exudates.
The local appilcation of REPICOL, on the skin surface, does not condece to seri levels higher that 0.1 meg/ml.

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