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 GRADUAL SLIMMING SAFETY. 
 SOME FAT INTAKE REMAINS REQUIRED. 

Key words:   Weight Loss, Cellulite, Fat-blockers, Enzyme-blockers, Weight Management, Overweight, Cholesterol blocking, Adipose cells, Uptake -control, Polysaccharide /carbohydrate digestion, Fast Food, Glycemic index GI, Ghrelin, Appetite restraining, Phaseolus, Chitosan, Inulin, Guar, Gymnema, Xhoba, Hoodia, Topinambur, Xenical, Insulin-mimic, Lipidplex, Opuntia/Nopal, Meridia, Reductil, Gallstones, Motility, Hypomotility, Saponification.

FAST WEIGHTLOSS can be a HEALTH HAZARD.

It has been known for over 30 years that forced weightloss can result in gallstone formation (Merckelbach 98 ). A good introduction is Eckel: Obesity, Ch12 98 ). When Eckel is not directly available, Everhart's Review: 100 ) "Contributions of Obesity and Weight Loss to Gallstone Disease" is accessible at the internet. It also offers an impressive list of references, many accessible through internet.
Since 15 years numeric data from ultrasonic screening have resulted in recom-mendations how to prevent stoneforming (lithogenesis) in the gallbladder.
Two relevant processes have been identified, one at the exit one at the entrance of the gallbladder:
1. Exit: the gallbladder contraction (=motility) to (partly) empty the bladder from gall (bile), is induced by the perceived content of fat in enjoyed meals or other food intake.
2. Entrance: the total amount of gall formed daily is adjusted to the history of diet habits of a person and can only slowly readjust to a structurally decreased fat consumption. (A diet in the medical sense is one's habitual food either freely chosen or restricted).
At the exit an implication of 1. for the motility is that some fat must be consumed daily. It was established in studies that 2 or 3 g fat /day is too little to cause sufficient contraction of the gallbladder (causing "hypomotility"),
this resulting in a high occurrence of gallstone formation due to unused bile. Use of 12 g fat/day (Anti-Aging-Guide - Your plan to stay young - CHOLECYSTITIS)  99 ) resulted in a low incidence of stone formation.
Prof GT Everson, Director Hepatology, Un Colorado Hospital, Denver, states "... as few as 10 g of fat (/day,RS) may be sufficient to maintain normal gallbladder contraction and emptying and thus reduce the risk of gallstone formation" (Eckel, Obesity, Ch12, § "Gallbladder Motility" Page 308 98 ).
Less amounts of grams of fat /day have been claimed in the literature to be sufficient but there might be a bandwidth depending on for example age and it seems wise to use the higher values mentioned, for the time being.
At the entrance if too much gall is produced and transferred to the gallbladder between meals/contractions still the risk of stone formation remains. That may happen when people are too eager to loose weight fast with one of the low calorie diet methods. It also is a well known complication after gastric bypass surgery.
In the case of diets it is easy to keep the weight loss /week below a limit. In the case of surgery when weightloss will occur quite fast, measures will be taken to force the bladder to contract, and to do that frequently.
Studies show that an accumulated (during some 6 months) weightloss as a percentage of total body weight must be kept below 24% (Everhart's Review: Contributions ..., § "Risk Factors for Gallstones with Weight Loss, see also Fig 1 ) 100 ). Above 24% the risk of stone formation rises. Further, the rate of weight change should be kept below 1.5 kg/wk Litiasis Biliar - Cálculos de Vesicula - Dietas Muy Bajas en Calorias § "Conclusionas", see also sideframe TIP for translation") 101 )
TIP
To translate Note 101., put Litiasis Biliar - Cálculos de Vesicula - Dietas Muy Bajas en Calorias in the miniwindow "search" of Google, press, then press "Translate this Page" for instant rough (like "biliary calculations" for "calculos biliares"=gall stones) translation.
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    WEIGHTLOSS in kg or in % ?    

 Weinsier 101 ) (Prof RL Weinsier, Director Clinical Nutrition Research Center, Un Alabama, Birmingham) advises that weightloss will not surpass 1.5 kg /week. However we comment it seems less appropriate to switch here from % to kg. 10 kg total weight loss for a 150 kg subject is not much, but for a 75 kg subject it is a lot. A simple calculation will show why % is to be preferred over kg.
Imagine a person accepts a plan for weightloss stretching over 6 months.
A practical, justified scheme would be:
  5 weeks first diet period;
5 weeks first restructure period;
5 weeks second diet period;
5 weeks sec'd restructure period;
5 weeks last diet period.
Total 25 weeks. In the 15 diet weeks, according to the 1.5 kg/week rule the person is allowed to loose 22.5 kg. If the person had an initial weight of 150 kg, the accumulated loss will be 15%, well below the limit of 24%. However when the person had an initial weight of 75 kg the accumulated loss would be 30%, unacceptable.
If however the "rule of thumb" would be set at a maximum of 1.5% /week the cumulated loss would be for the 150 kg person 33.75 kg, 22.5% in 6 months, for the 75 kg person, 22.5%, 16.9 kg. Both below the 24% limit and a weight loss to be proud of.