Table 1.FDA-Approved Treatment Options for H. pylori
  • Omeprazole 40 mg QD + Clarithromycin 500 mg TID x 2 weeks, then Omeprazole 20 mg QD x 2 weeks
  • Bismuth subsalicylate (Pepto Bismol) 525 mg QID + Metronidazole 250 mg QID + Tetracycline 500 mg QID* x 2 weeks + H2 receptor antagonist therapy as directed x 4 weeks
  • Ranitidine bismuth citrate (RBC) 400 mg BID = Clarithromycin 500 mg TID x 2 weeks than RBC 400 mg BID x 2 weeks
  • Bismuth subsalicylate (Pepto Bismal) 525 mg QID + Metronidazole 250 mg QID + Tetracycline 500 mg QID* x 2 weeks + H2 receptor antagonist therapy as directed x 4 weeks
  • Lansoprazole 30 mg BID + Amoxicillin 1 g BID + Clarithromycin 500 mg BID x 14 days
  • Lansoprazole 30 mg TID + Amoxicillin 1 g TID x 14 days**
  • *Although not FDA approved, amoxicillin has been substituted for tetracycline for patients in whom tetracycline is not recommended.
    **This dual therapy regimen has restrictive labeling, it is indicated for patients who are either allergic or intolerant to clarithromycin or for infections with known or suspected resistance to clarithromycin.




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    Copyright © 1997 Richard E. Randolph. Page created Monday, December 29, 1997 08:10 PM. Last updated Tuesday, February 10, 1998 8:40 PM .