The Use of Wavelets Transform in Medical Applications
               Heriot-Watt University
Department of Computing and Electrical Engineering 
 
  
by 
  Roslee Abdul Jalil
  
 
Objectives:  To analyse signal from the photoacoustic sensor and provide necessay signal conditoning for evaluation of blood glucose. 
 
Non Invasive Blood Glucose Monitor 
Diabetes, which afflicts as many as 15 million Americans, is one of the most prevalent of all chronic conditions.  Monitorting of Blood glucose is an important procedure for any diabetic subject.  A diabetic requires a daily routine of multiples finger stabs to obtain his blood glucose measurement.  Current technology is moving towards for non-invasive monitoring.  Such non-invasive method are laser spectroscopy or the near infra-red sensing method. 
 
PhotoAcoustic Spectroscopy 
When a pulse of laser light is absorbed by an analyte, the optical energy may be dissipated as heat which causes a sudden local temperature rise.  The subsequent thermal expansion generates a pressure waves which can be detected with a sensitve acoustic detector.  Photoacoustic spectroscopy is a long established technique which has been revitalized by the availability of new optoelectronic components from the telecommunication industry.This technique of sensing will be applied to the non-invasive measurement of blood glucose in the blood and the monitoring of oil in the water. The processing of data for the photoacoustic sensor will be carried out using wavelets transform.
 
Wavelet Transform 
Wavelet transform has become a powerful alternatives to Fourier Methods in many medical applications.  Fourier transform expands time domain signals into orthogonal basis functions (sines and cosines), thereby revealing the frequency content of the signals.  The frequency components are not localised in time and are best suited for describing  and analysing stationary signals.  Wavelet analysis expands signals into basis functions by expanding, contracting and shifting with a single prototype function.  Wavelet transform is an operation of decomosing a signal into different components that appear at different scales (or resolutions). 
 
 
MIPHACS Project 
Wavelets signal processing is part of the colloborated project from Micro Photo Acoustic Sensor Project MIPHACS group.  The main objective of the whole project is to established the technological basis for a new generation of analytical instruments based on monolithically integrated pulsed photoacoustic sensor.  The project objectives is to construct a modular instrument system which will have a high content of innovative optoelectronicand microsystem engineering with appropriate control and calibration software. 

This project is divided into various sections: 

Feasibility Studies of PhotoAcoustic Sensor for Medical Applications 
Wavelets Signal Processing on Medical Applications 
Sensor Design and Modelling 
  

 
Department of Physic 
Department of Computing and Electrical Engineering
 
 MIPHACS PROJECT GROUP
Project Supervisors :Dr Marc Philippe Yves Desmulliez  Dr Patrick Foulk 
Project Group Members 
Pang Ah Ju Roslee Abdul Jalil 
Ryan Porter   Chris Lupton  Chris Thomson  
Simon Fidders  John MacKenzie  
MIPHACS Group Email
 
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SURFING THE WAVELETS
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        Stanford University
Bibliography Collection of Daubechies
Non-invasive Blood Glucose Measurement Pages
Journal of Biomedical Optics 1(3), 280-288 (July 1996)
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This page is maintain by Roslee Abdul Jalil
Heriot-Watt Univeristy
Department of Computing and Electrical Engineering