The Sinister Six are a group of Spider-man's most deadly enemies. The original Sinister Six was brought together by Dr. Octopus in an effort to destroy Spider-man. However Spider-man defeated them all and sent them to prison. Years later Dr. Octopus recreated the Sinister Six and replaced Kraven with the second Hobgoblin. They tried to destory Spider-man, but failed again. Later after Dr. Octopus was killed by Kaine, Mysterio created the Sinister Seven to destroy Kaine, but they were defeated by both Kaine and Spider-man. Now after all this time a new Sinister Six has been brought together by the Sandman to destroy Spider-man, and there newest member is Venom.

Sinister Six I
Appearance: Amazing Spider-man Annual #1

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Dr. Octopus ........................Mysterio.......................Vulture

l........... .......................
Electro .............. Sandman ...............Kraven

Sinister Six II
Appearance: Amazing Spider-man vol 1, #334-339, Spider-man vol 1, # 18-23

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Dr. Octopus ...............Mysterio..........................Vulture

l........... .................
Electro ...................... Sandman ..................Hobgoblin II

Sinister Seven
Appearance: Spider-man Unlimited #9

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Mysterio .....................Scorpia......................Vulture

l........... .................
Electro ............ Shocker ...................Hobgoblin II

Beetle

Sinister Six III
Appearances: Amazing Spider-man vol 2, #12, Peter Parker: Spider-man vol 2, #12

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Venom .......................Mysterio II........................Vulture

l........... .................
Electro ................ Sandman ..................Kraven II


The Sinister Syndicate is a group composed of Spider-man's deadliest enemies by the Beetle. Originally created to destroy Spider-man, the second version of the syndicate was a group for hire by the mob. The third and last version of the Syndicate was to destroy Spider-man once again.

Sinister Syndicate I
Appearances: Amzing Spider-man vol 1, #280-281

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Beetle ................Rhino.......................Hydro-man

l...........

.................Speed Demon ............. Boomerang

Sinister Syndicate II
Appearances: Deadly Foes of Spider-man 1-4, Web of Spider-man Annual #8

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Beetle ......................Rhino.......................Blacklash

l........... .................
Speed Demon ................. Hydro-man ................Constrictor

Sinister Syndicate III
Appearances: Spider-man Unlimited #12

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Beetle ................Scorpia....................Boomerang

l...........

.................Shocker ............... Jack O' Lantern